TFLLRN-NH2 (CAS 244095-36-1) is a synthetic, amidated hexapeptide agonist of Protease-Activated Receptor 1 (PAR1/Thrombin Receptor). It is widely used in cell signaling, immunology, and thrombosis research. Basic Information: - Product Name: TFLLRN-NH2 - CAS No.: 244095-36-1 - Sequence: Thr-Phe-Leu-Leu-Arg-Asn-NH2 - Purity: ≥95% (HPLC) - Appearance: White to off-white lyophilized powder - Solubility: Soluble in water, PBS, or DMSO - Storage Conditions: -20°C, protect from light and moisture, avoid repeated freeze-thaw cycles Key Applications: 1. PAR1 receptor activation studies in platelets, endothelial cells, and other cell types 2. Thrombin receptor signaling and thrombosis research 3. In vitro studies of cell proliferation, migration, and inflammation mediated by PAR1 4. GPCR ligand screening and functional validation assays Advantages: - High purity and verified sequence integrity - Amidated C-terminus for enhanced stability and biological activity - Strict quality control with HPLC and mass spectrometry (MS) validation - Custom packaging available (mg scale) for research use For detailed specifications, solubility protocols, and bulk pricing information, please contact us directly.
