Recombinant Human VEGF121 (VEGF-A isoform 121) is a key angiogenic growth factor that plays critical roles in vascular development, angiogenesis, and tumor progression. The protein consists of 121 amino acids (Ala27–Arg147) and is expressed in HEK293 or E. coli systems, with high purity and verified bioactivity. Basic Information: - Product Name: Recombinant Human VEGF121 Protein - Synonyms: VEGF-A, VEGFA, VPF, Vascular Endothelial Growth Factor 121 - Accession No.: P15692-9 - Sequence: Human VEGF121 (Ala27–Arg147) - Expression System: HEK293 Cells / E. coli - Tag: His Tag / Untagged - Purity: ≥95% (SDS-PAGE & SEC-HPLC) - Endotoxin: <0.1–1 EU/μg (LAL) - Molecular Weight: ~14 kDa (monomer); ~36 kDa (homodimer) - Appearance: White lyophilized powder - Formulation: Lyophilized from sterile PBS, pH 7.4 - Storage: -20°C to -80°C; 12–24 months lyophilized, 3 months after reconstitution Key Applications: 1. Angiogenesis research & HUVEC proliferation assays (ED50 = 1–15 ng/mL) 2. VEGFR1/VEGFR2 binding & antibody neutralization studies 3. Oncology, inflammation, and vascular biology research 4. ELISA standards, Western blot, and functional cell-based assays 5. Drug discovery for anti-angiogenic therapies Advantages: - High purity & low endotoxin for cell-based assays - Strong bioactivity confirmed by HUVEC proliferation and receptor binding - Native-like folding (HEK293) or high yield (E. coli) options - Batch-to-batch consistency with full QC documentation (COA, SDS-PAGE, activity data) For COA, bulk pricing, custom tags or packaging, please contact us directly.
